At CBTEN, we hope to inspire students and researchers to explore the vast realms of Biomaterials and Tissue Engineering. Advancements in these fields are having a revolutionary impact on healthcare. Our online lectures and podcasts are therefore designed to; (1) enable an understanding of these subjects, by providing sound basic foundations, (2) share the cutting-edge advancements that are taking place in these fields and (3) keep up to date on the varied application of these subject disciplines, in the healthcare sector.
This lecture is designed to provide an introduction to the world of Biomaterials and Tissue Engineering.....
A very good review that summarizes how bioinspired materials are used for bone tissue engioneering, and also explores on their potential to model diseases of bone development and remodeling ex vivo.....
An interesting review that discusses all the recent advances made on material-based in situ valve tissue engineering and also provides a good perspective on the critical issues that need adressing to achieve its clinical application.....
This review is very informative. It provides an insight into the ‘Bio-inspired drug delivery systems’ for targeted cancer therapy.....
Coming Soon!
The need for sustainable medical therapeutics and diagnostics to treat ailment and disease affecting the normal functioning of the human body has never been so critical, especially considering the ever-increasing human population. To address, this issue of sustainable medical solutions, research on ‘biomaterials’ are increasingly taking a center stage. Biomaterials as the word suggest consist of two parts, ‘Bio’ and the ‘material’, so essentially, a biomaterial is any substance that has the capacity to interact with biological systems. The biomaterial, most of the time is engineered to take a form which either alone, or being part of a complex system, has the capacity to direct therapeutic or diagnostic procedures, by interacting with the components of the living i.e. biological systems. At CBTEN, research on exploring various material platforms (synthetic polymers, natural polymers, natural decellularised matrices, bioceramics and composite systems) as potential biomaterials will be a core part of the research activities.
Developing bioactive scaffolds that mimic native extracellular matrix (ECM) and is compliant to all the requirements of the target tissue/organ application, in terms of the microstructural, physicochemical, biomechanical in addition to being biocompatible and bioresorbable are critical parameters; all of which potentially determine the success of the therapeutic application. At CBTEN, development of bioactive scaffolds, that are able to best mimic native target tissue ECM and thus able to support the growth of native cell populations, will be one of the fundamental core areas of research. Various fabrication techniques like foaming, freeze drying, electrospinning, and 3D printing will be explored.
Assessing the properties of the developed biomaterials and/or scaffold is very important. These assessments would entail studying the biomaterials/scaffolds to characterize its microstructural (morphology, topography, surface roughness), physicochemical (chemical composition, wettability), mechanical, thermal, degradation rate and biocompatibility properties etc. All these characterisations will help to collect valuable data and insight about the material, which would be vital while tailoring the properties of the material to match those of native target tissue. At CBTEN therefore, assessing these properties of the biomaterials and scaffold will be an integral area of research. This will also lead to a greater understanding of the biomaterials and scaffolds being developed.
The long-term aspiration of CBTEN is to establish itself as a center of excellence for research in the fields of tissue engineering and regenerative medicine. With this long-term aspiration, the organization aims to provide a platform whereby students and researchers can explore and conduct cutting-edge research in exploring novel biomaterials, developing these materials into bioactive scaffolds and using this as a matrix to interact with cells to develop biological tissues. Using multidisciplinary and innovative approaches, we here at CBTEN continuously aspire to conduct research in the engineering of both hard (bone) and soft tissues (heart muscle, skin, cartilage etc) and regenerative medicine.